Validity of fibromyalgia survey questionnaire (2016) assessed by telephone interview and cross-cultural adaptation to Brazilian Portuguese language

Abstract Background: To verify the validity of the 2016-revised Fibromyalgia Survey Questionnaire (FSQ) by telephone interview compared to self-administration and to produce a valid version of FSQ in Brazilian Portuguese language. Methods: The Brazilian version of FSQ was produced following the recommendations for cross-cultural adaptation. Validity of Brazilian FSQ self-administration was assessed by checking agreement of its results with fibromyalgia diagnosis according the 1990 American College of Rheumatology (ACR) criteria. Reproducibility and validity of FSQ by telephone were assessed by comparing its results with the previous FSQ self-administration. Results: A Brazilian Portuguese version (FSQ-Brazil) was produced. FSQ-Brazil had good internal consistency (Cronbach's alpha between 0.73 and 0.94). Agreement between the results obtained by self-administration of FSQ-Brazil and by telephone interview was substantial or almost perfect for almost all questions about pain sites and all questions about other somatic symptoms (Cohen's kappa higher than 0.6). There were small but significant bias toward higher scores of widespread pain index and fibromyalgia severity scale in the telephone interview compared to self-administration. Fibromyalgia definition by self-administration and telephone interview with FSQ-Brazil both revealed substantial agreement with the diagnosis based on ACR 1990 criteria (Cohen's kappa 0.62 and 0.65; respectively). Conclusions: FSQ-Brazil demonstrated good internal consistency, reproducibility and validity both by self-administration and by telephone interview. However, caution must be taken with the interpretation of quantitative scores of widespread pain index and symptoms severity scale, which slightly differed according the method (self-administration or interview) in our study.(AU)

Avaliação do estado nutricional e do perfil clínico-epidemiológico dos pacientes em tratamento hemodialítico no Hospital São José de Criciúma e na Nefroclínica-Criciúma / Evaluation of the nutrition state and clinical and epidemiológico profile of patients in hemodialysis at Hospital São José de Criciuma and Nefroclinica-Criciuma

Objetivos Avaliar estado nutricional e perfil clínico-epidemiológico dos pacientes em tratamento hemodialítico no Hospital São José de Criciúma e na NefroclínicaCriciúma. Metodologia Estudo transversal, com análise de prontuários, entrevista e exame físico. Realizada avaliação nutricional pelo método de Avaliação Nutricional Subjetiva Global (SGA). As seguintes variáveis foram avaliadas: ferritina, colesterol total, uréia, creatinina, hemoglobina, paratormônio, idade, sexo, cor, tempo de diálise, classe sócio-econômica (CSE), causa da insuficiência renal crônica (IRC), doença cardiovascular, hepatite B e C. A análise estatística foi realizada através do teste-t, trabalhando com um nível de confiabilidade de 95%. Resultados Foram avaliados 103 pacientes, sendo 37 do Hospital São José e 66 da Nefroclínica. As causas de IRC mais prevalentes foram diabetes melito (44,66%) e hipertensão arterial sistêmica (25,24%). Apresentavam estado nutricional adequado (SGA=1) 8,3% dos pacientes e risco nutricional/desnutrição leve (SGA=2), 90,5%. A prevalência de anemia foi de 46,6% e de hepatite B e C, 4,8% e 5,8%. A prevalência de hiperparatireoidismo foi de 36,8% e a de doença cardiovascular (DCV) foi de 31%. Risco nutricional esteve relacionado ao maior tempo de diálise (p=0,008) e a menores níveis de uréia (p=0,03). Observou-se prevalência de DCV duas vezes maior nos pacientes desnutridos (SGA=2). Não houve relação entre CSE e estado nutricional. Conclusão A maioria dos pacientes avaliados apresenta desnutrição leve ou risco de desnutrição, independente da classesócio-econômica. Observou-se que: a principal causa de IRC terminal nestes pacientes é o DM; os níveis séricos de uréia podem estar associados à desnutrição e pacientes mal nutridos estão mais propensos a complicações cardiovasculares.

Objectives assess nutritional status and clinical and epidemiological profile of patients on hemodialysis treatment at the Hospital Sao Jose de Criciuma and Nefroclínica-Criciúma. Methodology Study cross, with analysis of records, interview and physical examination. Held nutritional assessment by the method of Nutrition Assessment Subjective Global (SGA). The following variables were analyzed: ferritin, total cholesterol, urea, creatinine, hemoglobin, parathormone, age, sex, color, length of dialysis, socio-economic classes (SEC), cause of chronic renal failure (CRF), cardiovascular disease, hepatitis B and C. The statistical analysis was performed by t-test, working with a level of reliability of 95%. Results were evaluated 103 patients, and 37 of St. Joseph Hospital and 66 of Nefroclínica. The causes of CRF were more prevalent diabetes mellitus (44.66%) and hypertension (25.24%). Presented adequate nutritional status (SGA = 1) 8.3% of patients and nutritional risk / mild malnutrition (SGA = 2), 90.5%. The prevalence of anaemia was 46.6% and hepatitis B and C, 4.8% and 5.8%. The prevalence of hyperparathyroidism was 36.8% and of cardiovascular disease (CVD) was 31%. Risk nutrition was related to the longer time of dialysis (p = 0008) and lower levels of urea (p = 0.03). It was observed prevalence of CVD two times higher in patients malnourished (SGA = 2). There was no relationship between SEC and nutritional status. Conclusion The majority of patients presenting mild malnutrition or risk of malnutrition, regardless of socio-economic classes. It was observed that: the main cause of IRC terminal in these patients is the DM; serum levels of urea can be associated with malnutrition and poorly nourished patients are more prone to cardiovascular complications.

Perfil dos pacientes com câncer diferenciado de tireoide em acompanhamentono ambulatório de Endocrinologia do Hospital Universitário de Florianópolis

Objetivo: O objetivo da pesquisa foi determinar o perfil clínico epidemiológico dos pacientes com câncer diferenciado de tireoide atendidos no Hospital Universitário de Florianópolis (HU-UFSC). Métodos: Tratou-se de estudo descritivo, realizado através da análise de prontuários. Incluídos pacientes com diagnóstico de câncer diferenciado de tireoide, em acompanhamento no Serviço de Endocrinologia de Hospital Universitário em consulta de setembro de 2009 a fevereiro de 2010. Considerou-se: idade ao diagnóstico, sexo, história familiar de câncer de tireoide, citologia pré-operatória (PAAF), histologia, tamanho tumoral,tipo de tireoidectomia; dose de I131, PCI (pesquisa de corpo inteiro), diagnóstico de hipoparatireoidismo póscirúrgico, níveis de tireoglobulina, anticorpo anti-tireoglobulina e TSH. Resultados: Foram avaliados 50 pacientes, sendo 92% mulheres. A média de idade foi de 48,5 anos. A prevalência de carcinoma papilífero e folicular foi de 92% e 8%, respectivamente. Hipoparatireoidismo ocorreu em 20% dos pacientes, sendo 8% permanente. Detectou-se evidência de doença ativa em 24% dos pacientes. Conclusões: Em nosso meio, o câncer de tireoide diferenciado é mais frequente em mulheres, sendo o papilífero o mais comum. O hipoparatireoidismo pós-cirúrgico definitivo é uma complicação importante encontrada em 8% dos casos.

Objective: The research aimed to determine the clinical and epidemiological profile in patients with differentiated thyroid cancer assisted at the University Hospital (HU-UFSC). Methods: The study was descriptive study by analysis of medical records. Included patients with differentiated thyroid cancer and followed at the Endocrinology Service of University Hospital from September 2009 to February 2010. Was considered: age at diagnosis, sex, family history of thyroid cancer, preoperative thyroid aspiration cytology, histology, tumor size, type of thyroidectomy, the dose of I131, whole body scan, post-surgical hypoparathyroidism, thyroglobulin, antithyroglobulin antibodies and TSH level. Results: We evaluated 50 patients, 92% women. The mean age was 48.5 years. The prevalence of papillary and follicular carcinoma was 92% and 8% respectively. Hypoparathyroidism occurred in 20% of patients, 8%permanent. Was detected evidence of active disease in 24% of patients. Conclusions: In our research, differentiated thyroid cancer is more common in women, with the papillary the most common. The post-surgical hypoparathyroidism is an important complication found in 8% of cases.

Avaliação tardia do eixo hipofisário-gonadal em pacientes adultos que sofreram traumatismo cranioencefálico grave / Late evaluation of the pituitary-gonadal axis in survivors of severe traumatic brain injury

OBJETIVO: Avaliar a função hipofisária-gonadal nos pacientes vítimas de TCE graves ocorridos na Grande Florianópolis, entre 2000 e 2004. MÉTODOS: Foram estudados 30 pacientes, sendo 22 homens e 8 mulheres, submetidos à avaliação clínica e laboratorial em seguimento médio de 4 anos após a data do traumatismo. RESULTADOS: Os homens possuíam em média 38 anos no ano da avaliação, enquanto as mulheres, 42 anos. A maioria dos traumatismos está relacionada aos acidentes de trânsito (63,3 por cento). Três pacientes (10 por cento) estavam com valores de FSH abaixo do normal e apenas 1 paciente (3,3 por cento) apresentou LH alterado. Nas mulheres avaliadas, os níveis de estradiol foram normais. Na população masculina, foi evidenciado nível de testosterona baixo em 2 pacientes (9,1 por cento). Todos os pacientes apresentavam normoprolactinemia. CONCLUSÃO: Dois casos de hipogonadismo masculino (9,1 por cento) foram diagnosticados neste estudo. Isso indica a necessidade de atenção aos pacientes sobreviventes de TCE grave para realizar diagnóstico precoce de hipogonadismo.

OBJECTIVE: The purpose of this study is to evaluate pituitary function impairment in order to verify the prevalence of sex hormone deficiency and to analyze the profile of TBI population. METHODS: Thirty patients were studied, 22 were male and 8 were female. All patients had their gonadal function assessed and they were evaluated at a median of 4 years post-trauma. RESULTS: The average age of the men was 38 years at the time of the evaluation, while the mean age of women was 42 years. The majority of TBI was related to traffic accidents (63.3 percent). Three patients (10 percent) had low FSH and only 1 patient (3.3 percent) had low LH. There was no biochemical evidence of hypogonadism in women. Two male patients presented low testosterone (9.1 percent) and were diagnosed with hypogonadism. Prolactin levels were normal in all patients. CONCLUSION: Two cases of hypogonadism (9.1 percent) were diagnosed among men in this study. It is therefore necessary that medical professionals involved in the management of TBI patients are aware of hypogonadism as a complication of TBI, in order to diagnose it early.